Shamilia Connell, Kyshona Knight, Natasha McLean and the uncapped fast bowler Jannillea Glasgow have been left out after being part of the squad against New Zealand, with the playing group downsized from 17 members to 14.
The series is an important one for both West Indies and England, who are looking to bounce back after defeats in their respective opening bouts of the 2022-25 ICC Women's Championship. While West Indies suffered a 2-1 loss to New Zealand, England were blanked 3-0 by India, with both defeats coming in home series.
The top five teams at the end of the 2022-25 cycle will qualify automatically for the 2025 ODI World Cup in India.
"This series against England comes on the heels of the New Zealand tour to the West Indies and continues our important preparation for the upcoming tri-series against India and South Africa and the ICC Women's T20 World Cup to follow," lead selector Ann Browne-John said. "It gives the players a great opportunity to develop and push for final selection for the tri-series and World Cup."
West Indies ODI squad: Hayley Matthews (capt), Shakera Selman (vc), Aaliyah Alleyne, Shemaine Campbelle (wk), Afy Fletcher, Cherry Ann Fraser, Shabika Gajnabi, Sheneta Grimmond, Chinelle Henry, Kycia Knight (wk), Chedean Nation, Karishma Ramharack, Kaysia Schultz, Rashada Williams