Healy will undergo scans on her calf when she returns to Australia later this week to determine the extent of the damage. Australia have home T20I and ODI series against Pakistan in mid-January ahead of the T20 World Cup in February.
McGrath was confident she could handle captaining her country after holding her nerve on Saturday and captaining Adelaide Strikers to the WBBL title last month.
"I'm new to leadership in this team and been learning a lot on the fly and it probably worked in my favour that I didn't have long to think about it," McGrath told reporters in Mumbai on Monday. "I was strangely calm out there, I had a lot of support. I had to try and stay calm and keep the team calm.
"I've come off the back of captaining Strikers for six weeks where it's high pressure. The best players in the world are there and that's what it felt like, I was captaining the Strikers with a few extra players."
Australia are undecided as to who will open alongside Mooney but they have plenty of options, including Litchfield and Ellyse Perry.
"We haven't decided yet," McGrath said. "But I think the good news is we've got a lot of options, whether Pheebs [Litchfield] comes in, she's done it in the Big Bash, myself, Pez [Perry]. We've got so many options but we'll have to wait and see."