England host 2019 champions Wales in the Six Nations at Twickenham on Saturday, needing to win to keep alive hopes of a third title in five years.

England make two changes with Mark Wilson coming in for injured flanker Sam Underhill and Anthony Watson replacing Jonathan Joseph on the wing.

Wales face England under head coach Wayne Pivac for the first time having lost successive Six Nations matches.

They make four changes from the home defeat by France two weeks ago.

Scarlets-bound back Liam Williams makes a first appearance since the World Cup after recovering from an ankle problem.

Cardiff flanker Josh Navidi, who has been injured since January, is preferred to Taulupe Faletau at number eight, and Rob Evans replaces fellow Scarlets prop Wyn Jones in the front row.

Cardiff scrum-half Tomos Williams makes a first appearance against England, with Gareth Davies dropping out of the squad altogether, while Bath nine Rhys Webb, Saracens prop Rhys Carre and Scarlets flanker Aaron Shingler all come onto the bench.

Commentator's notes

BBC Sport's Eddie Butler: The double blip of defeats against South Africa and France has turned into a back-to-back recovery against Scotland and Ireland.

England are back on track with a vengeful determination and have home advantage against Wales to boot. Or to pass, or to drive. Any which way they like. They look formidable.

Wales have lost their last two games and are fully aware that England are never the easiest to face when your timing is a little off and your title has already slipped away. But there's nothing like the prospect of humiliation to concentrate the mind. Wales are close to being excellent.

Having predicted high-scoring adventures in all rounds, this time both teams are going to deliver. England 39-38 Wales.

View from both camps

England head coach Eddie Jones: "You've got to remember they beat us last year so we owe them one.

"They've lost two games in a row. They've got a new coach and they'll want to make a statement on Saturday.

"Traditionally our games are very close so they'll come with a lot of enthusiasm and a lot of energy."

Wales head coach Wayne Pivac: "We've had a good two weeks and we are really excited about heading up to Twickenham for what will be a huge Six Nations clash.

"We have had the chance to put the disappointments of the loss to France behind us, and we know we need to be more clinical in attack and convert the opportunities that we are creating.

"Liam's return to full fitness is a positive after the loss of Josh Adams, as is the return of Josh Navidi."

Line-ups

England: 15- Elliot Daly; 14-Anthony Watson, 13-Manu Tuilagi, 12-Owen Farrell (capt), 11-Jonny May; 10-George Ford, 9-Ben Youngs; 1-Joe Marler, 2-Jamie George, 3-Kyle Sinckler, 4-Maro Itoje, 5-George Kruis, 6-Courtney Lawes, 7-Mark Wilson, 8-Tom Curry

Replacements: 16-Luke Cowan-Dickie, 17-Ellis Genge, 18-Will Stuart, 19-Joe Launchbury, 20-Charlie Ewels, 21-Ben Earl, 22-Willi Heinz, 23-Henry Slade

Wales: 15-Leigh Halfpenny; 14-George North, 13-Nick Tompkins, 12-Hadleigh Parkes, 11-Liam Williams; 10-Dan Biggar, 9-Tomos Williams; 1-Rob Evans, 2-Ken Owens, 3-Dillon Lewis, 4-Jake Ball, 5-Alun Wyn Jones (capt), 6-Ross Moriarty, 7-Justin Tipuric, 8-Josh Navidi

Replacements: 16-Ryan Elias, 17-Rhys Carre, 18-Leon Brown, 19-Aaron Shingler, 20-Taulupe Faletau, 21-Rhys Webb, 22-Jarrod Evans, 23-Johnny McNicholl

Match facts

Head-to-head

England

Wales

Match officials

Referee: Ben O'Keeffe (New Zealand)

Touch judges: Romain Poite (France) & Alexandre Ruiz (France)

TMO: Marius Jonker (South Africa)