Britain's Joe Salisbury and Neal Skupski were both beaten in their men's doubles quarter-final ties in Paris.
Salisbury, 30, and American Rajeev Ram, 38, lost to Ivan Dodig and Austin Krajicek 3-6 7-6 (11-9) 7-6 (12-10).
The top seeds wasted five match points in all as Dodig and Krajicek edged the final set tie-break.
Skupski, 32, and Dutch partner Wesley Koolhof, 33, were seeded sixth, but lost to fourth seeds Marcel Granollers and Horacio Zeballos 3-6 6-3 6-4.