He is batting third and playing third base in Tuesday night's game against the Minnesota Twins, who lead the Guardians by just one game in the AL Central standings.
Franmil Reyes also is back in the lineup for the Guardians, batting sixth as the designated hitter. Reyes, who was activated from the injured list on Tuesday, was placed on the IL with a tight right hamstring on May 26.
Civale, who was placed on the IL May 25 with left glute tightness, is starting Tuesday night's game against the Twins.
Ramirez, who has an eight-game hitting streak, leads the AL with 62 RBIs and his .305 batting average is ninth in the AL.