"He's obviously a key player for us."
In that match he also claimed Shan Masood in the penultimate over to further showcase his versatility at the death. He won't be easy to replace if ruled out with Mills, David Willey and Chris Jordan fighting for a berth alongside speedster Mark Wood and Sam Curran, who starred against Australia with clutch death bowling marked by canny slower deliveries.
While Woakes and Topley were originally earmarked to be England's new-ball bowlers, Willey could now be a powerplay option along with Ben Stokes, who recently returned to T20Is after an 18-month absence.
England have already been dealing with the headache of losing Topley on tournament eve, in what is a significant blow, given his flexibility and versatility to bowl at every phase.
"We're all so bitterly disappointed for him," Buttler said of Topley, whose 17 T20I wickets is the most by an England bowler this year.
"The amount of setbacks he has had already in his career...to come back and be in the position he's in on the eve of a tournament, being in such great form, and to have that cruelly taken away from him is really tough."
Even though England have entered the tournament with bad injury luck, much like 12 months ago, there is an air of confidence in their camp that has been evident since they initially arrived in Perth earlier in the month.
It manifested in an impressive series victory over Australia, which probably would have been a clean sweep if not for a washout in Canberra, but Buttler has managed expectations in his first major tournament in charge.
"Far from it," Buttler said when asked if he believed England were favourites, preferring to give the tag to Australia. "I think we're a dangerous team who have players who can win games on their own and that's a huge thing in T20 cricket.
"We have plenty of options as to whichever way we want to go. I'm very confident in the team."