Wales have injury worries over fly-half Gareth Anscombe and scrum-half Tomos Williams after their World Cup warm-up defeat by England.

Anscombe and Williams will both have scans on Monday, for knee and shoulder injuries.

Anscombe 28, had to come off because of his knee in the 33-19 loss at Twickenham, while Williams, 24, was a late withdrawal.

Flanker Justin Tipuric, 30, limped off with an ankle problem but should be OK.

Ospreys' Anscombe was helped off late in the first half and later seen on crutches on the sidelines.

Wales coach Warren Gatland said Anscombe will undergo a scan to determine the extent of the damage.

"We're not sure about Gareth," said Gatland.

"He's going to get a scan tomorrow [Monday] so we'll see how that turns out.

"I've spoken to the physios. If it's just a strain of the ligament, he'll be out for a few weeks. We'll know more details after the scan."

Gatland said the medical advice during the game was to allow Anscombe the chance to overcome the injury after the initial blow.

"The message from the medics was just to see how it goes. He didn't do any further damage to it. He's already done that," Gatland added.

"Sometimes players like to run off a knock - he wasn't able to do that.

"That's why with Justin Tipuric we made the change as soon as we saw him limping a little bit.

"There's a risk, but you have to be battle hardened as well, and the guys want to play. You have to balance that against the injuries you may pick up."

Blues scrum-half Williams was initially named as a replacement for the Twickenham match but was pulled out after suffering an injury in training on Friday.

Wales have a rematch with England in Cardiff on Saturday, 17 August followed by another double-header against Ireland in Cardiff on 31 August and 7 September in Dublin as they prepare for the World Cup in Japan.

In the build-up to the game, Gatland said criticism of Wales playing four warm-ups was "fair".

After the defeat at Twickenham that denied Wales top spot in the World Rankings, he told BBC Sport: "There's a risk, but you have to be battle hardened as well, and the guys want to play.

"You have to balance that against the injuries you may pick up."

In Japan, Wales' Pool D campaign begins against Georgia in Tokyo on Monday, 23 September followed by games against Australia, Fiji and Uruguay.