South Australia 7 for 438 dec (Drew 208*, Hunt 62, McAndrew 56*) and 2 for 31 lead Western Australia 162 (Stoinis 56, McAndrew 3-51, Agar 3-54) by 307 runs
SA ended day two at Adelaide Oval on 2 for 31, giving them an overall lead of 307. Drew, unbeaten on 208 when SA declared at 7 for 438 at lunch, was trapped lbw for 4 by Matthew Kelly in the final over of the day.
Drew accumulated 25 boundaries in his 345-ball first innings, which far exceeded his previous best first-class score of 130.
He featured in an unbroken eighth-wicket stand of 78 with McAndrew, who blasted four sixes in an innings of 56 off 59 balls.
With Western Australia in to bat, McAndrew and fellow paceman Agar claimed the first six wickets between them, with the visitors skittled for 162, a deficit of 276.
WA were 2 for 5 after two early strikes by Agar and lost 3 for 0 to slump to 6 for 63 after Cameron Bancroft and Aaron Hardie each made 27. They were reeling again at 7 for 71 shortly after tea.
In South Australia's first innings - pacemen Stobo and Kelly apart - the WA attack struggled, with David Moody leaking 129 of 28 wicketless overs and spinner Corey Rocchiccioli taking 1 for 135 off 32.
Batting for the second time towards the end of play on Saturday, SA had Jake Carder caught at short cover off Stoinis for 8 before losing Drew to the second ball of the final over.