Lunch South Africa 320 and 69 for 4 (Bavuma 35*, Mayers 2-10) lead West Indies 251 by 138 runs
A disciplined display of seam and swing bowling helped West Indies go to lunch on the third day at Wanderers in a strong position, as they left South Africa four wickets down and with a lead of just 138.
Mayers was entrusted to bowl the first over on Friday, and he made instant impact. Dean Elgar, who was out ramping to deep third in both innings at SuperSport Park, tried to steer him through point but got an edge to Roston Chase who took a good catch at gully.
Jason Holder started from the other end and, in his second over of the day, troubled Tony de Zorzi. He drew an outside edge, which didn't carry to second slip, and then beat the outside edge the very next ball.
But de Zorzi, who had scored an impressive 85 in the first innings, did not last too long as he chopped on Mayers' first delivery in the fifth over of the day.
It was once again Markram who stood up for South Africa. Unlike in the second innings of the first Test, when he came out all guns blazing, he was very watchful. He left anything that was wide but made sure to pounce on the bad deliveries.
At one stage, Markram was on 3 off 27 balls, before picking up his first boundary with a straight drive off a Mayers inswinger. A few overs later, he cover-drove Roach and then clipped Holder through midwicket for two more fours. In between, there was an inducker from Holder that grazed his pad as he shouldered arms. West Indies used the DRS but the ball-tracking showed the ball would have missed the stumps.
Having played out 55 deliveries with great assurance, it took a jaffa from Roach to get him to nick behind to Joshua Da Silva. Roach angled one in on a length outside off and Markram had to play at it, but the ball straightened to take a thin outside edge.
Temba Bavuma then led South Africa's recovery as he and Ryan Rickelton put on 37 runs for the fourth wicket. The two batted for an hour, and started to pick up some runs as well. Bavuma played some flicks both behind and in front of square as he moved to 35.
But Reifer, with his left-arm medium pace, earned the reward for his disciplined spell as he got Rickelton to nick off at the stroke of lunch.