Wales have made five starting changes for their Six Nations finale against Italy in Parma on Saturday.
Head coach Ioan Cunningham starts with 14 players involved in the bonus-point wins against Ireland and Scotland.
The front row of Gwenllian Pyrs, Kelsey Jones and Sisilia Tuipulotu are back in the XV, with flanker Alex Callender returning in the back row.
Keira Bevan is given the nod at scrum-half to partner fly-half Elinor Snowsill.
Lleucu George keeps her place at centre, while wing Ameila Tutt is set to make her debut off the bench and become the fourth player to win her first cap during the tournament.
Centre Kerin Lake is selected on the bench after recovering from a calf injury picked up against Scotland.
Experienced prop Caryl Thomas is also named on the bench after her wife gave birth to a daughter earlier this month.
Both sides will be looking to bounce back following setbacks in round four, Wales after a 39-14 defeat to France and Italy after a 29-21 defeat against Scotland.
Wales are in a commanding position to finish third in this year's championship. They only need a point to guarantee their place in the top tier of World Rugby's new WXV competition this autumn.
Scotland must beat Ireland with a bonus point and overturn a significant points difference to finish above them.
"Our goal at the start of the Six Nations was to have two wins heading into the final game against Italy," Cunningham said.
"We have made no secret of the fact that we have targeted three wins in this tournament.
"We have shown against two of the best sides in the world, England and France, that we can compete with the best, but know we need an 80-minute performance in Parma.
"Italy have won the last two games against us and are two places above us in the world rankings, but we are excited about the challenge ahead of us."
Italy: Vitorria Ostuni Minuzzi; Aura Muzzo, Michela Sillari, Beatrice Rigoni, Alyssa D'Inca; Veronica Madia, Sara Barattin (capt); Gaia Maris, Vittoria Vecchini, Lucia Gai, Valeria Fedrighi, Giordana Duca, Sara Tounesi, Isabella Locatelli, Giada Franco.
Replacements: Emanuela Stecca, Alice Cassaghi, Alessia Pilani, Laura Gurioli, Alissa Ranuccini, Sofia Stefan, Emma Stevanin, Beatrice Capomaggi.
Wales: Courtney Keight; Lisa Neumann, Hannah Jones (capt), Lleucu George, Carys Williams- Morris; Elinor Snowsill, Keira Bevan; Gwenllian Pyrs, Kelsey Jones, Sisilia Tuipulotu, Abbie Fleming, Georgia Evans, Bethan Lewis, Alex Callender, Sioned Harries.
Replacements: Carys Phillips, Caryl Thomas, Cerys Hale, Bryonie King, Kate Williams, Ffion Lewis, Kerin Lake, Amelia Tutt.