Third seed Daniil Medvedev needed just 74 minutes to cruise into the second round of the US Open with a dominant win over Attila Balazs.

Despite his brilliant win on Arthur Ashe Stadium, the Russian said he "does not care" all the attention is firmly on Novak Djokovic and Carlos Alcaraz.

The emerging rivalry of top two seeds Alcaraz and Djokovic has dominated the build-up to the men's event.

"It's normal they're the biggest names right now," Medvedev, 27, said.

"I don't care. My goal is to try to play well to get to wherever they are and try to win."

Medvedev will play the winner of the all-Australian encounter between Max Purcell and Christopher O'Connell for a spot in the last 32.

But Medvedev's compatriot and 11th seed Karen Khachanov was upset 6-2 6-4 6-2 by American Michael Mmoh.

Elsewhere on day two, 12th seed and 2020 finalist Alexander Zverev beat Australian Aleksandar Vukic 6-4 6-4 6-4.

Former Wimbledon finalist Matteo Berrettini beat French 29th seed Ugo Humbert 6-4 6-2 6-2.

The Italian will face another Frenchman in Arthur Rinderknech in the second round after he beat Argentina's Diego Schwartzman 6-3 6-4 6-2.