FORT LAUDERDALE, Fla. -- Inter Miami suffered a stunning first-round elimination from the 2024 Major League Soccer playoffs after falling 3-2 against Atlanta United in Game 3 of their Eastern Conference series at Chase Stadium on Saturday night.

Lionel Messi looked to have rescued Miami after scoring a second-half headed equalizer, but Bartosz Slisz won the game and the series for Atlanta with a 76th-minute header.

The goal was scored while Miami defender Tomás Avilés was down on the field in his own penalty area, with his teammates appealing for the referee to stop the game to allow him to receive treatment.

Messi twice had chances to level the score with free kicks, but on both occasions his efforts were blocked by the Atlanta wall as Miami fell victim to arguably the biggest upset in MLS playoff history.

Led by the Argentina star, Miami entered the postseason as the No. 1 seed after setting the MLS record for most points in a season to earn its first Supporters' Shield. But it fell short against an Atlanta side that finished as the No. 9 seed in the Eastern Conference, 34 points behind Miami, and qualified for the postseason only with a final-day win to clinch a wild-card spot.

The Herons defeated Atlanta in the first game at home before losing Game 2 at Mercedes-Benz Stadium in Atlanta that forced a decisive third game.

And Miami again struggled against the Five Stripes on Saturday. Though Matías Rojas gave Miami the lead in the 17th minute, Jamal Thiare quickly found the equalizer minutes later. Atlanta then took a 2-1 lead within seconds after a second strike from Thiare.

Miami, which amassed 79 goals in 34 regular-season games, including 20 each from Messi and Luis Suárez, would get back on level terms through Messi. But defensive frailties and a standout performance from Atlanta's 40-year-old goalkeeper, Brad Guzan, saw a star-studded Miami team exit the postseason to dramatically conclude its 2024 season.

Atlanta will face Orlando City in the conference semifinals.

The team with the best record won the MLS Cup four times in the league's first seven seasons. In the 22 seasons since, the top overall seed has gone on to win the title only four more times.

The loss extended Miami's struggles in the MLS postseason, with the team co-owned by David Beckham still never progressing beyond the first round.

The South Florida team first featured in the MLS postseason in its inaugural 2020 season, losing 3-0 to Nashville in the play-in round. Two years later, the Herons fell 3-0 to New York City FC in the first round.

Miami missed the playoffs last season after Messi's midyear arrival but expected far more this year with a full season of a team featuring not only eight-time Ballon d'Or winner Messi but his one-time Barcelona teammates Suárez, Sergio Busquets and Jordi Alba as well as a former Barcelona coach in Gerardo Martino.

Messi's $20,446,667 in total compensation from Inter Miami this season was about $5 million more than the entire Atlanta payroll, and Inter Miami spent a record $41.7 million on payroll this season.

Miami will now shift focus to building its roster for 2025, when it will compete in the expanded 32-team Club World Cup.

Though Suárez's contract is set to expire at the end of this year, the forward revealed there have been negotiations between his agent and the club to extend his time in South Florida.

Messi's deal with Miami will see him play one more season at Chase Stadium.

Information from The Associated Press contributed to this report.