To help you set your lineups and avoid starting a player who won't take the field, we will post fantasy-relevant updates and analysis here as NFL teams release their inactives lists, typically about 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Refresh often for the latest information.
1 p.m. ET games
Offense
David Johnson, RB, ARI: Ankle -- Questionable
Impact: Game-time call. Chase Edmonds would start if he can't go.
Christian Kirk, WR, ARI: Ankle -- Questionable
Impact: Also a game-time call. Damiere Byrd is the safer play.
A.J. Green, WR, CIN: Ankle -- OUT
Impact: Seemingly still not close to return. Tyler Boyd and Auden Tate remain fantasy-viable.
Geronimo Allison, WR, GB: Concussion -- Questionable
Impact: Upgraded on Saturday, but still risky.
Davante Adams, WR, GB: Toe -- OUT
Impact: Jake Kumerow/Allen Lazard become flex longshots.
Marquez Valdes-Scantling, WR, GB: Ankle -- Questionable
Impact: At best, a game-time call, which behooves you to have a Plan B.
Marqise Lee, WR, JAX: Ankle -- OUT
Impact: Chris Conley should handle No. 3 WR duties.
Dede Westbrook, WR, JAX: Shoulder -- Questionable
Impact: Game-time call. If he sits, Keelan Cole might get a few looks.
Geoff Swaim, TE, JAX: Concussion -- OUT
Impact: Josh Oliver primed to make his NFL debut.
Malcolm Brown, RB, LAR: Ankle -- Doubtful
Impact: Todd Gurley II will be back in the huddle in the nick of time.
Jakeem Grant, WR, MIA: Hamstring -- Questionable
Impact: Albert Wilson, who is also dinged up, is the best of the sad Miami WR bunch.
Sterling Shepard, WR, NYG: Concussion -- OUT
Impact: Limited practices, but won't clear protocol. Go with Golden Tate/Darius Slayton instead.
Tyrell Williams, WR, OAK: Foot -- OUT
Impact: Trevor Davis, Hunter Renfrow are among potential replacements ...
Dwayne Harris, WR, OAK: Ankle -- Questionable
Impact: ... as would be Zay Jones and Keelan Doss.
Deebo Samuel, WR, SF: Groin -- OUT
Impact: Not traveling with team. Dante Pettis/Marquise Goodwin get minor value bumps.
Raheem Mostert, RB, SF: Knee -- Questionable
Impact: With Tevin Coleman back from injury, Mostert's fantasy value is all but zero.
Chris Thompson, RB, WAS: Toe -- OUT
Impact: Wendell Smallwood should be quite active in the passing game.
Vernon Davis, TE, WAS: Concussion -- OUT
Impact: Jeremy Sprinkle hasn't done much with his window of opportunity thus far.
Defense
Zach Allen, DE, ARI: Neck -- OUT
Desmond Trufant, CB, ATL: Toe -- OUT
Matt Milano, LB, BUF: Hamstring -- Questionable
Taron Johnson, CB, BUF: Hamstring -- Questionable
Carlos Dunlap, DE, CIN: Knee -- Doubtful
Darius Slay, CB, DET: Hamstring -- Questionable
Quandre Diggs, S, DET: Hamstring -- Questionable
Kenny Clark, DT, GB: Calf -- Questionable
Darnell Savage, S, GB: Ankle -- OUT
Johnathan Joseph, CB, HOU: Hamstring -- Questionable
Tashaun Gipson Sr., S, HOU: Hip -- Questionable
Bradley Roby, CB, HOU: Hamstring -- Questionable
Justin Houston, DE, IND: Calf -- Questionable
Malik Hooker, S, IND: Knee -- Doubtful
Kenny Moore II, CB, IND: Knee -- OUT
Pierre Desir, CB, IND: Abdomen -- Questionable
Reshad Jones, S, MIA: Chest -- OUT
Xavien Howard, CB, MIA: Knee -- Questionable
Ben Gedeon, LB, MIN: Concussion -- OUT
Arden Key, DE, OAK: Kneecap -- OUT
D.J. Jones, DT, SF: Hamstring -- OUT
Ahkello Witherspoon, CB, SF: Foot -- OUT
Josh Norman, CB, WAS: Thigh -- Questionable
4 p.m. ET games
Offense
Marquise Brown, WR, BAL: Ankle -- Questionable
Impact: Missed practice all week. Willie Snead IV/Miles Boykin both benefit if he's out.
Mitchell Trubisky, QB, CHI: Shoulder -- Questionable
Impact: Practiced in full pads all week, so it would be a surprise if he didn't start this one.
Michael Badgley, K, LAC: Groin -- Questionable
Impact: If he is able to suit up, one would have to be fearful of rust.
Drew Brees, QB, NO: Thumb -- OUT
Impact: Next week is a real possibility. Teddy Bridgewater is to be avoided, given all the other offensive injuries.
Alvin Kamara, RB, NO: Ankle -- OUT
Impact: It will be Latavius Murray, early and often and all of the time.
Tre'Quan Smith, WR, NO: Ankle -- OUT
Impact: Deonte Harris/Lil'Jordan Humphrey become deep-league dart throws.
Jared Cook, TE, NO: Ankle -- OUT
Impact: Dan Arnold promoted from practice squad.
Will Dissly, TE, SEA: Achilles -- OUT
Impact: Out for the year. Luke Willson will try to pick up the slack.
Delanie Walker, TE, TEN: Ankle -- Questionable
Impact: Jonnu Smith is as good as dice roll as any, should Walker sit.
Defense
Patrick Onwuasor, LB, BAL: Ankle -- Questionable
Bilal Nichols, DE, CHI: Knee -- Questionable
Melvin Ingram III, DE, LAC: Hamstring -- Doubtful
Brandon Mebane, DT, LAC: Knee -- OUT
Justin Jones, DT, LAC: Shoulder -- OUT
Ziggy Ansah, DE, SEA: Ankle -- Questionable
Bradley McDougald, S, SEA: Back -- Questionable
Jayon Brown, LB, TEN: Groin -- Doubtful
Cameron Wake, LB, TEN: Hamstring -- Questionable
Official Sunday inactives should begin coming in at approximately 11:30 a.m. ET for the early games and at 2:30 p.m. ET for the late games.