To help you set your lineups and avoid starting a player who won't take the field, we will post fantasy-relevant updates and analysis here as NFL teams release their inactives lists, typically about 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Refresh often for the latest information.
1 p.m. ET games
Offense
David Johnson, RB, ARI: Ankle -- Questionable
Impact: Not expected to play this week or next. Chase Edmonds will try to repeat last week's stellar outing.
Christian Kirk, WR, ARI: Ankle -- Questionable
Impact: Game-time call. Trent Sherfield and Damiere Byrd will still feature prominently.
Matt Ryan, QB, ATL: Ankle -- OUT
Impact: Matt Schaub will start, lowering the value of all Atlanta receivers.
Ito Smith, RB, ATL: Concussion -- OUT
Impact: Brian Hill will back up Devonta Freeman.
Duke Williams, WR, BUF: Shoulder -- Questionable
Impact: Isaiah McKenzie/Andre Roberts could see slight upticks in value.
A.J. Green, WR, CIN: Ankle -- OUT
Impact: It's the "Auden Tate and Alex Erickson Show" in Cincinnati again.
Jack Doyle, TE, IND: Groin -- Questionable
Impact: Eric Ebron would be a strong TE1 candidate if Doyle has to sit.
Dede Westbrook, WR, JAX: Neck -- Questionable
Impact: Expected to play, which would give Gardner Minshew II another solid target.
Justin Jackson, RB, LAC: Calf -- Questionable
Impact: Austin Ekeler shouldn't have to worry about anyone else stepping in to spell Melvin Gordon.
Keenan Allen, WR, LAC: Hamstring -- Questionable
Impact: Geremy Davis and Andre Patton could become flex options if Allen, as expected, doesn't play.
Michael Badgley, K, LAC: Groin -- Questionable
Impact: Chase McLaughlin will kick in his place.
Malcolm Brown, RB, LAR: Ankle -- OUT
Impact: Darrell Henderson Jr. emerges as strong fantasy flex in London.
Drew Brees, QB, NO: Thumb -- Questionable
Impact: Expected to start ahead of the bye week. Saints wouldn't do so if there were any questions about his fitness.
Alvin Kamara, RB, NO: Ankle -- Questionable
Impact: Don't expect to see him suit up. Latavius Murray is more than capable of handling RB duties this week.
Tre'Quan Smith, WR, NO: Ankle -- OUT
Impact: Austin Carr gets slight fantasy boost.
Jared Cook, TE, NO: Ankle -- OUT
Impact: Josh Hill gets a chance to take advantage of a really good TE matchup.
Sterling Shepard, WR, NYG: Concussion -- OUT
Impact: Golden Tate/Darius Slayton are the team's top WR options.
Braxton Berrios, WR, NYJ: Hamstring -- Questionable
Impact: This is the week Demaryius Thomas needs to step up and lock out Berrios from the Jets' huddle.
Chris Herndon, TE, NYJ: Hamstring -- OUT
Impact: Ryan Griffin will start in his place.
Darren Sproles, RB, PHI: Quad -- OUT
Impact: Good news if you were planning to start either Jordan Howard or Miles Sanders.
DeSean Jackson, WR, PHI: Abdomen -- OUT
Impact: Neither Nelson Agholor nor Mack Hollins have been able to break out while Jackson continues to sit.
O.J. Howard, TE, TB: Hamstring -- OUT
Impact: Cameron Brate becomes a strong TE option.
Delanie Walker, TE, TEN: Ankle -- OUT
Impact: Jonnu Smith has a solid matchup and might be able to shine this week.
Defense
Zach Allen, DE, ARI: Neck -- OUT
Jordan Hicks, LB, ARI: Calf -- Questionable
Haason Reddick, LB, ARI: Knee -- Questionable
Desmond Trufant, CB, ATL: Toe -- OUT
Matt Milano, LB, BUF: Hamstring -- Questionable
Bilal Nichols, DE, CHI: Knee -- Questionable
Darqueze Dennard, CB, CIN: Hamstring -- OUT
Justin Hollins, LB, DEN: Knee -- Questionable
Bryce Callahan, CB, DEN: Foot -- OUT
Damon Harrison Sr., DT, DET: Groin -- Questionable
Darius Slay, CB, DET: Hamstring -- OUT
Pierre Desir, CB, IND: Hamstring -- Questionable
Kenny Moore II, CB, IND: Knee -- Questionable
Leon Jacobs, LB, JAX: Hamstring -- OUT
Quincy Williams, LB, JAX: Hamstring -- OUT
Brandon Mebane, DT, LAC: Knee -- OUT
Justin Jones, DT, LAC: Shoulder -- OUT
Melvin Ingram III, DE, LAC: Hamstring -- Questionable
Bryce Hager, LB, LAR: Shoulder -- OUT
Troy Hill, CB, LAR: Hamstring -- Questionable
Henry Anderson, DE, NYJ: Shoulder -- Questionable
Neville Hewitt, LB, NYJ: Neck -- Doubtful
C.J. Mosley, LB, NYJ: Groin -- OUT
Trumaine Johnson, CB, NYJ: Ankle -- Questionable
Tim Jernigan, DT, PHI: Foot -- OUT
Nigel Bradham, LB, PHI: Ankle -- OUT
Avonte Maddox, CB, PHI: Concussion -- OUT
Ziggy Ansah, DE, SEA: Ankle -- Questionable
Quandre Diggs, S, SEA: Hamstring -- Questionable
Tre Flowers, CB, SEA: Neck -- Questionable
Adoree' Jackson, CB, TEN: Foot -- OUT
4 p.m. ET games
Offense
Cam Newton, QB, CAR: Foot -- OUT
Impact: No controversy this week as Kyle Allen gets the start.
Will Fuller V, WR, HOU: Hamstring -- OUT
Impact: Kenny Stills hopes to continue to success he had last week against the Colts.
Rex Burkhead, RB, NE: Foot -- Questionable
Impact: Injury keeps James White somewhat fantasy relevant.
Julian Edelman, WR, NE: Chest -- Questionable
Impact: Expected to play. Just a reminder that Josh Gordon is on IR.
Matt LaCosse, TE, NE: Knee -- OUT
Impact: Ben Watson has likely taken over starting role going forward...
Ryan Izzo, TE, NE: Concussion -- OUT
Impact: ... though arrival of Mohamed Sanu diminishes the need for massive TE targets.
Josh Jacobs, RB, OAK: Shoulder -- Questionable
Impact: Expected to play, but Jalen Richard should still see enough work to matter.
Tyrell Williams, WR, OAK: Foot -- Questionable
Impact: Expected to play, with Zay Jones on the opposite side of field.
Raheem Mostert, RB, SF: Knee -- Questionable
Impact: Matt Breida appears ready to return, but Tevin Coleman may be the better RB play.
Marquise Goodwin, WR, SF: Personal -- Questionable
Impact: Beyond Emmanuel Sanders, there's no 49ers WR reliable enough to start in fantasy.
Defense
Damarious Randall, S, CLE: Ankle -- OUT
Tashaun Gipson Sr., S, HOU: Ankle -- Questionable
Bradley Roby, CB, HOU: Ankle -- Questionable
Patrick Chung, S, NE: Concussion -- Questionable
Ahkello Witherspoon, CB, SF: Toe -- OUT
Official Sunday inactives should begin coming in at approximately 11:30 a.m. ET for the early games and at 2:30 p.m. ET for the late games.