Indianapolis Colts wide receiver T.Y. Hilton will not play Sunday against the Pittsburgh Steelers, because of a calf injury that could keep him out multiple weeks, according to coach Frank Reich.

Reich said the noncontact injury occurred in practice Wednesday, and that the injury generally keeps a player out three to four weeks. The coach said he did not believe Hilton would need surgery.

The Colts are 0-5 without Hilton since he entered the NFL in 2012. Hilton missed the Colts' Week 4 loss to the Oakland Raiders because of a quad injury.