To help you set your lineups and avoid starting a player who won't take the field, we will post fantasy-relevant updates and analysis here as NFL teams release their inactives lists, typically about 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Refresh often for the latest information.
1 p.m. ET games
Offense
Chase Edmonds, RB, ARI: Hamstring -- OUT
Impact: David Johnson returns, with Kenyan Drake as stellar support.
Damiere Byrd, WR, ARI: Team decision -- Inactive
Impact: Andy Isabella may have earned himself an increase in playing time.
Ito Smith, RB, ATL: Neck -- OUT/IR
Impact: Brian Hill/Kenjon Barner become handcuff material.
Lamar Jackson, QB, BAL: Illness -- Active
Impact: Will start after returning to practice late in week.
Marquise Brown, WR, BAL: Ankle -- Active
Impact: Willie Snead IV is left in limbo.
Duke Williams, WR, BUF: Team decision -- Inactive
Impact: Second straight week. Feel free to remove from fantasy rosters.
Adam Shaheen, TE, CHI: Team decision -- Inactive
Impact: Trey Burton to get the majority of TE looks.
A.J. Green, WR, CIN: Ankle -- OUT
Impact: At this point, IR looms. Alex Erickson maintains his flex-level fantasy value.
Ricky Seals-Jones, TE, CLE: Knee -- Inactive
Impact: Demetrius Harris should see uptick in value with Seals-Jones sitting.
Antonio Callaway, WR, CLE: Team decision -- Inactive
Impact: Very surprising call. Combined with Kareem Hunt in backfield, this may signal a run-heavy attack today.
Matthew Stafford, QB, DET: Back, Hip -- Inactive
Impact: Detroit will not let him play today. Jeff Driskel will start. Lower all Lions in value.
LeSean McCoy, RB, KC: Team decision -- Inactive
Impact: Darrel Williams/Darwin Thompson to potentially handle backup duties.
Sterling Shepard, WR, NYG: Concussion -- OUT
Impact: At this point, there's no real reason to expect a return.
Evan Engram, TE, NYG: Foot -- OUT
Impact: Rhett Ellison takes over, but it's the Giants' WRs who should see extra looks.
Le'Veon Bell, RB, NYJ: Knee -- Active
Impact: Bell will play and is expected to receive his usual workload.
Demaryius Thomas, WR, NYJ: Hamstring -- Active
Impact: He has played through the injury for several weeks, but Sam Darnold is still his QB.
Chris Herndon, TE, NYJ: Hamstring -- Active
Impact: He is suiting up, but Ryan Griffin has done very well while he has been away.
Corey Davis, WR, TEN: Hip -- Inactive
Impact: A.J. Brown gets an opportunity to step up.
Delanie Walker, TE, TEN: Ankle -- OUT
Impact: Jonnu Smith has been averaging four catches per game.
Defense
Zach Allen, DE, ARI: Neck -- OUT
Terrell Suggs, LB, ARI: Hamstring -- Active
Deionte Thompson, S, ARI: Knee -- Inactive
Desmond Trufant, CB, ATL: Toe -- Inactive
Earl Thomas III, S, BAL: Knee -- Active
Eddie Goldman, DT, CHI: Thigh -- Active
Olivier Vernon, DE, CLE: Knee -- OUT
Damarious Randall, S, CLE: Hamstring -- Active
Damon Harrison Sr., DT, DET: Groin -- Active
A'Shawn Robinson, DT, DET: Ankle -- Active
Romeo Okwara, DE, DET: Groin -- Inactive
Tracy Walker, S, DET: Knee -- OUT
Alex Okafor, DE, KC: Ankle -- OUT
Frank Clark, DE, KC: Neck -- Active
Kendall Fuller, CB, KC: Thumb -- Inactive
Steve McLendon, DT, NYJ: Neck -- Active
Henry Anderson, DE, NYJ: Shoulder -- Active
Neville Hewitt, LB, NYJ: Neck -- Inactive
C.J. Mosley, LB, NYJ: Groin -- OUT
Jordan Jenkins, LB, NYJ: Calf -- Active
Darryl Roberts, CB, NYJ: Calf -- Inactive
Carl Nassib, DE, TB: Groin -- OUT
Carlton Davis, CB, TB: Hip -- OUT
Jurrell Casey, DE, TEN: Shoulder -- OUT
Jayon Brown, LB, TEN: Groin -- OUT
4 p.m. ET games
Offense
Jacoby Brissett, QB, IND: Knee -- OUT
Impact: Brian Hoyer may well be able to do some damage against Miami, but ...
T.Y. Hilton, WR, IND: Calf -- OUT
Impact: ... Zach Pascal is the only real WR option here, as Parris Campbell also misses time.
Brandin Cooks, WR, LAR: Concussion -- OUT
Impact: He has been cleared to practice, so next week seems like a possible target for return.
James Conner, RB, PIT: Shoulder -- OUT
Impact: Jaylen Samuels likely to receive the majority of carries.
Benny Snell Jr., RB, PIT: Knee -- OUT
Impact: Trey Edmunds practiced late in week and should provide RB backup.
JuJu Smith-Schuster, WR, PIT: Foot -- Questionable
Impact: Diontae Johnson/James Washington would see additional targets if he can't go.
Defense
Vernon Butler, DT, CAR: Back -- Questionable
James Bradberry, CB, CAR: Groin -- Questionable
Adrian Amos, S, GB: Hamstring -- Questionable
Jaire Alexander, CB, GB: Groin -- Questionable
Pierre Desir, CB, IND: Hamstring -- Doubtful
Bryce Hager, LB, LAR: Shoulder -- OUT
Davon Godchaux, DT, MIA: Shoulder -- Questionable
Reshad Jones, S, MIA: Chest -- OUT
Ken Webster, CB, MIA: Ankle -- OUT
Official Sunday inactives should begin coming in at approximately 11:30 a.m. ET for the early games and 2:30 p.m. ET for the late games.