Flanker Mark Wilson and wing Anthony Watson will make their first England appearances since the Rugby World Cup after being named to start against Wales in the Six Nations on Saturday.
Wilson, who has recovered from knee injury, joins Courtney Lawes and Tom Curry in the back row.
Watson is back after a calf problem and replaces Jonathan Joseph.
Eddie Jones has again named six forwards on the bench but there is no Sam Underhill in the 23.
England team to face Wales:
Daly; Watson, Tuilagi, Farrell, May; Ford, Youngs; Marler, George, Sinckler, Itoje, Kruis, Lawes, Wilson, Curry
Replacements: Cowan-Dickie, Genge, Stuart, Launchbury, Ewels, Earl, Heinz, Slade
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