The Big Ten will play a 10-game, conference-only football schedule that begins Labor Day weekend and includes ample flexibility, the league announced Wednesday morning.

Each team has two open weeks, and the schedule has four weeks built in to reschedule games. The model allows for Week 1 and Week 2 games to be moved to later in the season.

The regular season is set to wrap up Nov. 21 with an open date for all teams on Nov. 28, and the league championship game is set for Dec. 5 with the ability to move it back a week or two.

The football schedule starts as early as the weekend of Sept. 5 with final games slated for Nov. 21 to align with academic calendars. The Big Ten Football Championship Game remains scheduled for Dec. 5 at Lucas Oil Stadium, though it could be moved as late as Dec. 19. pic.twitter.com/vWp3OSifBc

— Big Ten Conference (@bigten) August 5, 2020

Michigan and Ohio State will face each other Oct. 24 -- the first time since 1942 that the rivals will not play at the end of the regular season. The Indiana-Purdue game, pitting rivals from opposite divisions, will take place Nov. 21.

The Big Ten also announced medical protocols, including twice-weekly testing for COVID-19. The league will use a third-party laboratory to conduct centralized testing and "consistency in surveillance and pre-competition testing."

The Big Ten on July 9 became the first FBS conference to reveal a general scheduling model, saying that all of its fall sports, including football, would operate with a league-only slate. But the league had held off on announcing specifics for football as it evaluated medical information about the coronavirus pandemic.

Maryland announced Wednesday that it was preparing to begin the season without spectators in attendance, but "it is our hope that we may be able to welcome some fans to home games as the season progresses and health conditions permit."