Wales and Dragons centre Jamie Roberts has tested positive for coronavirus just a few days before the planned resumption of the Pro14 season.
Last month Roberts joined Dragons who are due to face Ospreys on Sunday, 23 August, a day after Scarlets host Cardiff Blues.
The centre is in good health but has been placed into isolation and will not play this weekend.
The players were tested on Tuesday with results expected on Wednesday.
If there are a number of positive tests among the Dragons squad, the match against Ospreys will be in doubt.
Roberts, 33, had returned to Wales from a short stint with Stormers in South Africa.
In April, the qualified doctor volunteered to help the National Health Service fight against coronavirus and became involved with the Cardiff and Vale Health Board in a communication and promotional role.
The centre, who has 94 Wales caps, completed his medical degree from Cardiff University in 2013.
A Dragons statement said: "Dragons rugby has returned a positive case for Covid-19 in Welsh rugby's testing programme in the round of tests taken week, commencing Monday, 11 August.
"All subsequent Public Health Wales and Government guidelines are being followed and the individual - who is symptom free and in good health - is currently isolating.
"Dragons rugby is part of the wider Welsh Rugby Union screening programme, which has conducted over 1,100 tests to date as part of the return to training/playing process."