England prop Mako Vunipola has been ruled out of his side's Autumn Nations Cup final against France at Twickenham on Sunday with an Achilles problem.

Ellis Genge is promoted from the bench into the starting XV, with Joe Marler joining the replacements.

"Mako picked up an injury in last week's game," said England's attack coach Simon Amor.

"We've given him every opportunity to recover for this one but unfortunately he hasn't made it."

Vunipola had re-established himself as England's first choice loose-head prop after Marler missed the start of the autumn because of a knee injury.

"It's disappointing to lose any player," added Amor. "In Ellis Genge and Joe Marler we've got two outstanding loose-heads there. They've trained well this week.

"Ellis is a real bowling ball in terms of his carries, so he'll bring that aggression with the ball.

"He's a very destructive scrummager and he brings a real energy to the team. He's a great one to bring in."

Line-ups

England: Daly; Watson, Slade, Farrell (capt), May; Ford, Youngs; Genge, George, Sinckler, Itoje, Launchbury, Curry, Underhill, B Vunipola.

Replacements: Cowan-Dickie, Marler, Stuart, Hill, Earl, Robson, Malins, Marchant.

France: Dulin; Raka, Moefana, Danty, Villiere; Jalibert, Couilloud; Kolingar, Bourgarit, Aldegheri, Geraci, Pesenti, Woki, Jelonch, Tofofua.

Replacements: Mauvaka, Neti, Atonio, Ducat, Macalou, Bezy, Carbonel, Barassi.