Tasmania 4 for 225 (Silk 69, Wright 66) beat Victoria 222 (Handscomb 95, Harper 51, Andrews 3-45) by six wickets
Jordan Silk and Mac Wright added 126 as Tasmania secured a comfortable victory against an inexperienced Victoria side that had earlier collapsed from a strong position.
A century stand between Sam Harper and captain Peter Handscomb had taken the home side to 1 for 128 in the 22nd over but they then lost 9 for 94 with the spin of Tom Andrews and Beau Webster taking five wickets.
Andrews, the left-arm spinner, struck twice in an over to start the major unravelling of Victoria's innings as Matt Short drove to cover then Jake Fraser-McGurk was given lbw second ball.
Handscomb's outstanding form continued as he tried to hold the innings together but he lost partners regularly. MacKenzie Harvey, another of the young players Victoria are given a chance to, lofted into the deep and Xavier Crone was run out by a direct hit.
Searching to bring up his century with a six, Handscomb was well held on the deep midwicket rope by Silk who parried the ball back in before he touched the rope and gathered the rebound.
Victoria managed an early breakthrough when Caleb Jewell pulled high into the leg side and when spinners Todd Murphy and Will Parker both picked their first wickets on one-day debut Tasmania were 3 for 90.
However, there were precious other alarms as Wright and Silk took charge of the chase against the young bowling attack on a docile surface. Another debutant, Brody Couch, who went at under three an over was able to claim his first wicket when Wright was caught at long leg from a top-edged hook but by then the game was done.