Ready for another day of March Madness? How's your bracket? The first round of the 2021 NCAA tournament continues Saturday.

Friday's first-round games were not kind to the Big Ten. The league lost two top-four seeds (Ohio State and Purdue). According to ESPN Stats & Information, that was the first time that had happened to the league since the tournament expanded in 1985.

The day wasn't kind to the ACC either. The league had four teams lose (Clemson, UNC, Georgia Tech and Virginia Tech) on the same day in the NCAA tournament for the first time in conference history. But, Buddy Buckets and Syracuse went off.

Here's a look at the best stuff from Saturday's NCAA tournament action:

Down go the defending champs!

For the second time in three NCAA tournaments, the Virginia Cavaliers have been upset in the first round. This time, the loss came at the hands of the 13th-seeded Ohio Bobcats. The Cavs are the fourth reigning champ to be eliminated in round of 64 (UConn 2012, UCLA 1996 and Indiana 1988), per ESPN Stats & Information.

Ohio dethrones the defending champs! ?@OhioMBasketball | #MarchMadness pic.twitter.com/N1Sy6a8zcw

— NCAA March Madness (@marchmadness) March 21, 2021

The game wasn't without its nerves for Bobcats fans, though.

Do you have your emotional support buddy, @OhioMBasketball fans? pic.twitter.com/XJGEWf0sRn

— March Madness TV (@MarchMadnessTV) March 21, 2021

Big 3s and clutch free throws helped send the Bobcats to the next round. It was the team's third straight opening-round victory in the NCAA tournament.

pic.twitter.com/VZi6iqEqVy

— Ohio Basketball (@OhioMBasketball) March 21, 2021

The win was a reminder that another team from the state of Ohio deserves respect.

THE. OHIO. UNIVERSITY. ?#MarchMadness pic.twitter.com/46EEBJvQ3T

— NCAA March Madness (@marchmadness) March 21, 2021

The Jabari Walker show

Colorado absolutely dusted Georgetown. It was the Buffaloes' biggest NCAA tournament win, according to ESPN Stats & Information.

Freshman Jabari Walker had a career-high 24 points and was 5-of-5 from the 3-point line, his most 3s in a game in his career and a Colorado NCAA tournament single-game record. Walker hadn't even attempted four 3s in a game before Saturday. Teammate D'Shawn Schwartz also hit 5 threes Saturday and now shares that record with Walker.

McKinley Wright IV had 13 assists, a CU tournament record. That included 8 assists in the first half alone. In the previous six NCAA tournaments, only one player had at least 13 assists in a game: Murray State's Ja Morant in 2019 (16).

Socially distant Madness

Unprecedented times call for new solutions. The Gonzaga Kennel Club found a unique way to bring the game to the fans.

March Madness in Covid times. @ZagKennelClub is hosting an outdoor watch party here on campus where students were able to register in groups of 6 for socially distant pods to catch the game on a 27' outdoor screen. pic.twitter.com/TddvB9GXtP

— Austin Getz (@AustinGetzTV) March 21, 2021

Garden State pride

It's no question who the New Jersey Devils are rooting for after seeing UConn junior R.J. Cole's shoulder, especially after Rutgers already advanced on Friday.

We feel the love, @rjuice_.#MarchMadness | #JerseyPride pic.twitter.com/zIwSYR72lu

— New Jersey Devils (@NJDevils) March 21, 2021

Boom-er Sooner

Oklahoma controlling both ends ✋@OU_MBBall | #MarchMadness pic.twitter.com/skWvgFOtDa

— NCAA March Madness (@marchmadness) March 20, 2021

Big-time jams!

MILES NORRIS THROWING IT DOWN ?@UCSBbasketball | #MarchMadness pic.twitter.com/CXamN6U1kS

— NCAA March Madness (@marchmadness) March 20, 2021

BISHOP REVERSE ?@BluejayMBB |#MarchMadness pic.twitter.com/ZywVkvRTPO

— NCAA March Madness (@marchmadness) March 20, 2021

Michigan's Isaiah Livers' sideline fashion statement

Isaiah Livers in the #NotNCAAProperty shirt FTW pic.twitter.com/IkTBBrKOFr

— Tammi Gaw (@tammigaw) March 20, 2021

Eastern Washington's burgeoning cult heroes

No. 14 seed EWU put up a fight against No. 3 seed Kansas. That was in large part thanks to the Groves brothers. Tanner (the bearded star of Saturday) had 35 points and Jacob had 23.

The Groves bros are filling it up for EWU! ?@EWUMBB | #MarchMadness pic.twitter.com/jGIvSyw5XD

— NCAA March Madness (@marchmadness) March 20, 2021

2nd 16:55 | More great ball movement by the Eags leads to a Tanner Groves triple! He's got all seven for Eastern so far in the second half!

? 51
? 17#GoEags #BigSkyinBoise pic.twitter.com/vyazWD76BG

— EWU MBB (@EWUMBB) March 13, 2021

Early top plays

Florida State hates rims ?@FSUHoops | #MarchMadness pic.twitter.com/x9rVaHB7cS

— NCAA March Madness (@marchmadness) March 20, 2021

The Buffs drained 11 threes in the first half ?@CUBuffsMBB | #MarchMadness pic.twitter.com/HOA1NY6Dha

— NCAA March Madness (@marchmadness) March 20, 2021

WHOLE SQUAD HYPED! ???@CUBuffsMBB #MarchMadness pic.twitter.com/qtz3O2jYYJ

— NCAA March Madness (@marchmadness) March 20, 2021

Michigan's managers doing work

They don't call them our managers THE LEADERS & BEST for nothing! #GoBlue 〽️?#MarchMadness#ForCompetitorsOnly pic.twitter.com/ZVIGJUAYxj

— Michigan Men's Basketball (@umichbball) March 20, 2021

We are all this drummer today

#MarchMadness energy right here pic.twitter.com/Ka8Hak7ogb

— Kansas Jayhawks (@KUAthletics) March 20, 2021

Football shoutouts

Wishing @CoachEwing33 and the Hoyas good luck in the Tournament! #HoyaSaxa x #MarchMadness https://t.co/sW8ZqqUOP5 pic.twitter.com/iEUECWLqKu

— Washington Football Team (@WashingtonNFL) March 20, 2021

Time to dance, @FSUHoops & @fsuwbb!!#NoleFamily | #MarchMadness pic.twitter.com/08EitIY6Ro

— FSU Football (@FSUFootball) March 20, 2021

Here's what else you missed on Friday:

16 Games.
3 OTs.

What a day. ? #MarchMadness pic.twitter.com/4Lc16RCUvf

— NCAA March Madness (@marchmadness) March 20, 2021