Britain's Jamie Murray and Brazilian partner Bruno Soares were knocked out of the French Open in the third round.
The seventh seeds, bidding for a third Grand Slam title together, lost 6-3 3-6 6-3 to Germany's Kevin Krawietz and Romania's Horia Tecau.
There is little rest for Murray, who returns later on Saturday in the mixed doubles with American partner Bethanie Mattek-Sands.
They take on Mexico's Giuliana Olmos and Colombia's Juan Sebastian Cabal.
Fellow Briton Neal Skupski also plays in the mixed doubles alongside Chilean Alexa Guarachi against Chan Hao-ching and John Peers.
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