Minnesota Twins third baseman Josh Donaldson responded sharply to Chicago White Sox starter Lucas Giolito on Wednesday, one day after Giolito called him a "pest" and "classless" after the slugger appeared to yell, "Not sticky anymore," following a first-inning home run in Tuesday night's game.

"He called me a pest, right?" Donaldson said on a lengthy videoconference with reporters Wednesday afternoon. "Which is fine. I kind of almost consider that a compliment.

"He calls me classless? I didn't think I was showing him up during the game. I was talking to my bench. I wasn't pimping my home run. I wasn't talking to him, saying anything."

Donaldson has been one of baseball's most outspoken sluggers when it comes to pitchers using sticky substances, which the league recently started cracking down on. He said Giolito's response to Donaldson's post-homer comment spoke volumes.

"Obviously, he showed offense to what I said, which I think kind of speaks more about the looming question that's going on, which is, was he using sticky stuff before all of this happened in the first place?" Donaldson said. "If he wasn't, then he probably wouldn't have cared about that comment."

The feud began on Tuesday night after Donaldson homered off of Giolito. While crossing the plate, Donaldson rubbed his hands together and could be heard saying, "Hands not sticky anymore." That prompted Giolito to call him out after the game.

"He's a f---ing pest," Giolito said Tuesday night. "That's kind of a classless move. If you're going to talk, talk to my face."

Donaldson said he sought out Giolito in the Guaranteed Rate Parking lot after the White Sox's 7-6 win. The Twins veteran was asked Wednesday about that meeting.

"He didn't have really much to say," Donaldson said. "He said that he thought I was annoying. I said, 'So what? I'm on the opposing team. What do you care about me?' I said, 'I'm in your face. I'm telling you what I think. What have you got to say about that?' And he didn't have any response."

Giolito gave up three runs on six hits and a walk over six innings to get his first win in a month.

Donaldson said he saw a difference in Giolito's stuff Tuesday night with the league now inspecting pitchers for foreign substances, including claims that the Sox ace's spin rates were lower.

"I didn't see any swings and misses on fastballs up yesterday where he normally gets swings and misses up there. ... That's where you get that hopping effect from the spin rate," Donaldson said. "The slider yesterday, he had a couple swings and misses, but I hit a ball to right field off of him and a ball to left field off of him that I felt like I just missed and I felt like I put some pretty good passes on it and I felt like some other guys put some good swings on them."

Donaldson was also upset with White Sox television analyst and former manager Ozzie Guillen, who suggested during a postgame show that Giolito should "drill" Donaldson with a pitch the next time they face each other.

"And I got Ozzie Guillen talking s--- on the air saying that, 'I'd let one go, hit him in the ribs,'" Donaldson said. "Ozzie Guillen, you were under a career .700 OPS hitter, man. You were a three-time All-Star and you had an under .700 OPS. My worst season in the big leagues is 150 points higher than that.

Donaldson added: "People need to start realizing -- you talk about 95, 98 mph balls getting thrown at people's ribs and seeing guys from New York [Yankees] say the same s--- about me? 'Oh, hit him in the ribs.' Hey, I'm just trying to make the game fair. I didn't make the rules."

Donaldson added some fuel to the rivalry Wednesday night. After homering in his first at-bat off White Sox starter Dylan Cease, he dropped his bat at the plate and took a few moments to admire his shot before rounding the bases to a chorus of boos from Chicago fans.

The White Sox and Twins close out their series Thursday and play again next Monday through Wednesday in Minnesota.