Robbie Henshaw will make his first appearance of the season as one of four changes to Ireland's starting XV to face Argentina on Sunday.
While the pack remains the same, Henshaw is named at inside centre with Bundee Aki missing out through a minor knee injury.
Ulster's Robert Baloucoune starts on the wing in place on Andrew Conway.
Joey Carbery and Conor Murray form the half-back duo with Johnny Sexton and Jamison Gibson-Park both ruled out.
Head coach Andy Farrell has resisted the temptation to make wholesale selection changes in a bid to maintain the momentum built by his side.
Having named the same team for the wins against Japan and the All Blacks, just one of the changes made this week is unforced.
Centre Henshaw is recalled after he sustained a foot injury upon return from the British and Irish Lions tour, during which he started all three Tests.
"In my experience world class players generally can come back in without too much game time," said Farrell.
"He has been in and around camp and he has looked great in training in past few days. I think he will add to the performance."
He resumes his Leinster midfield partnership with Garry Ringrose, who was one of Ireland's star performers in their impressive success last Saturday.
It is a second cap for Ulster wing Baloucoune after the 24-year-old marked his debut in the summer with a scintillating try against the USA.
With regular captain Sexton ruled out for up to six weeks with an ankle injury, Carbery gets the start having come on to kick three late penalties and help Ireland over the line against New Zealand.
Harry Byrne is named among the replacements with no place for Jack Carty who was brought in as extra cover.
Having been so impressive in the two autumn wins, the pack remains unchanged, with Iain Henderson partnering stand-in captain James Ryan in the second row in between all-Leinster front and back rows.
Farrell wary of 'unorthodox' Argentina
Argentina arrive in Dublin having snapped a seven-game losing streak by defeating Italy last week.
The Pumas made history last November by beating the All Blacks for the first time, and are hoping to claim a first win in Dublin on Sunday.
"They can be unorthodox opponents and offload the ball at unexpected moments," Farrell said.
"We have got to be aware of the fact they beat the best team in the world and they have beaten us in big matches in the past.
"They have come to Dublin mindful they have not had a result here before which should spur them on. We are expecting a full on battle."
Three Argentina changes
Argentina have made three personnel changes to their starting XV which beat the Italians 37-19 in Treviso last weekend.
Head coach Kieran Crowley has recalled Guido Petti and Santiago Grondona to his pack, while Lucio Cinti replaces Santiago Cordero on the wing.
Petti's inclusion at lock leads to a reshuffle among the forwards, with Marcos Kremer moving into the back row alongside Grondona and Pablo Matera, who switches from blindside flanker to number eight on the occasion of his 80th Test.
In the backline, Cinti will line up on the left flank, meaning Mateo Carreras switches to the right. Uncapped Exeter back Facundo Cordero could make his international debut from the bench.
Argentina have never won in Dublin - suffering defeat on each of their previous nine visits - but have recorded three World Cup victories over their hosts.
Ireland: Keenan; Baloucoune, Ringrose, Henshaw, Lowe; Carbery, Murray; Porter, Kelleher, Furlong, Henderson, Ryan; Doris, van der Flier, Conan.
Replacements: Sheehan, Healy, O'Toole, Beirne, O'Mahony, Casey, Byrne, Earls.
Argentina: E Boffelli; M Carreras, M Moroni, J De La Fuente, L Cinti; S Carreras, T Cubelli; T Gallo, J Montoya (capt), F Gomez Kodela, G Petti, T Lavanini, S Grondona, M Kremer, P Matera.
Replacements: F Bosch, I Calles, E Bello, L Paulos, I Facundo, G Bertranou, N Sanchez, F Lamb.