MIAMI -- The NBA postponed Wednesday's game between Miami and San Antonio, after the combination of injuries and positive tests left the Heat unable to meet the league's requirement of eight available players.

It was the 10th game postponed in the NBA this season because of virus-related issues. None have been rescheduled.

Miami had 12 players listed as out for the game against the Spurs for a variety of reasons. The Heat beat Washington on Tuesday night with only eight players available -- and of those, only five would have been able to play Wednesday in San Antonio.

Gabe Vincent, who played 35 minutes in Tuesday's win, learned after the game that he had a positive test and couldn't travel. Jimmy Butler was ruled out for Wednesday after spraining his right ankle with about a minute left in the Wizards' game, and KZ Okpala was unable to play because of an injury he sustained Tuesday as well.

The Heat had also added P.J. Tucker and Zylan Cheatham, neither of whom played Tuesday, to the protocols. And Tuesday's game came after Miami guard Max Strus -- who had been feeling no symptoms -- was pulled after he warmed up, because of a positive test that required his entering the protocols.

"That's the perplexing thing about this right now, this variant," Heat coach Erik Spoelstra said. "I think we've gotten to a point -- I've said it before -- we need more information. Are there more asymptomatic cases? All of this is with the caveat of double vaccination, with a booster and then asymptomatic, what does that mean and what adjustments can we make there? ... I think it leads to a lot of confusion."

Miami had tried to get roster help Wednesday -- ironically -- from the Austin Spurs, San Antonio's G League affiliate, in part because those players could get to San Antonio relatively quickly and in time to play. Miami was in the process of signing Austin center Aric Holman to a hardship contract Wednesday, and likely will need more reinforcements before its next scheduled game Friday in Houston.

Almost every team in the NBA has been dealing with virus-related issues in recent days, with more than 120 players and five head coaches in the protocols entering Wednesday.

"The whole league's going through this," Spoelstra said.

The league told teams early Wednesday that it was amending its protocols again, this time to shorten the required amount of time a player who tests positive needs to spend in isolation to five days -- following guidance released by the U.S. Centers for Disease Control and Prevention. The league made that disclosure in a memo obtained by The Associated Press.

The five-day isolation is predicated on the player either being asymptomatic or having his symptoms resolved by the fifth day. That change doesn't necessarily mean a player could return to the court more quickly, because the updated CDC guidelines also call for an additional five days of wearing a mask when around others after leaving isolation.

But it does allow teams, when a player or staffer tests positive on a road trip and must begin isolating immediately, the ability to use commercial airlines to fly that person home sooner than had been the case in some instances while the 10-day isolation period was in effect.

The Associated Press contributed to this report.