CLEVELAND -- Philadelphia 76ers All-Star center Joel Embiid left Wednesday night's game against the Cleveland Cavaliers in the first quarter and was ruled out with a left shoulder sprain.
Embiid appeared to collide with Cavaliers center Ante Zizic while being fouled late in the first quarter. The 7-footer held his shoulder when he went to the foul line and was in obvious pain as he missed two free throws.
Embiid was removed at the next time stoppage and walked to the locker room. He briefly returned to the bench in the second quarter but then went back to the locker room.
Embiid, who scored a career-high 49 points Monday against Atlanta, is averaging 23.8 points and 12 rebounds.
Philadelphia is also playing without All-Star guard Ben Simmons, who missed his second straight game because of a nerve impingement in his lower back.
The Associated Press contributed to this report.