Novak Djokovic faces deportation again after the Australian government revoked his visa for a second time, the latest twist in the ongoing saga over whether the No. 1-ranked tennis player will be allowed to compete in the Australian Open despite being unvaccinated for COVID-19.

Immigration Minister Alex Hawke said Friday that he used his ministerial discretion to cancel Djokovic's visa on public interest grounds -- just three days before play begins at the Australian Open, where Djokovic has won a record nine of his 20 Grand Slam titles.

Three hours later, Djokovic's lawyers began their appeal against the visa cancellation in an after-hours hearing at the Federal Circuit and Family Court. The same judge, Anthony Kelly, ruled in favor of Djokovic earlier this week on procedural grounds after his visa was first canceled when he landed at a Melbourne airport.

Djokovic's lawyer Nick Wood told Kelly he hoped that an appeal will be heard Sunday and that Djokovic, who is from Serbia, would have his visa returned in time for him to play Monday, when the top half of the draw is set to compete.

Djokovic, 34, remains free Friday night but would effectively return to immigration detention when he meets with Australian Border Force officials at 8 a.m. Saturday (4 p.m. ET Friday).

He would spend the morning at his lawyers' offices under Border Force guard and return to hotel detention Saturday afternoon.

Deportation from Australia can lead to a three-year ban from the country, although that might be waived, depending on the circumstances.

Hawke said he canceled the visa on "health and good order grounds, on the basis that it was in the public interest to do so." His statement added that Prime Minister Scott Morrison's government "is firmly committed to protecting Australia's borders, particularly in relation to the COVID-19 pandemic."

Djokovic's main ground of appeal against Hawke's decision was that it was not based on the health risk that the tennis champion might pose by not being vaccinated but on how he might be perceived by anti-vaxxers.

"The minister only considers the potential for exciting anti-vax sentiment in the event that he's present," Wood said.

Hawke's reasons do not take into account the potential impact on anti-vaxxers of Djokovic being forcibly removed, Wood said.

"The minister gives no consideration whatsoever to what effect that may have on anti-vax sentiment and indeed on public order," Wood said. "That seems patently irrational."

Morrison welcomed Djokovic's pending deportation. The whole episode has touched a nerve in Australia, particularly in Victoria state, where locals went through hundreds of days of lockdowns during the worst of the pandemic and there is a vaccination rate among adults of more than 90%.

Australia is facing a massive surge in coronavirus cases driven by the highly transmissible omicron variant. On Friday, the nation reported 130,000 new cases, including nearly 35,000 in Victoria state. Although many infected people aren't getting as sick as they did in previous outbreaks, the surge is still putting a severe strain on the health system, with more than 4,400 people hospitalized. It's also causing disruptions to workplaces and supply chains.

"This pandemic has been incredibly difficult for every Australian, but we have stuck together and saved lives and livelihoods. ... Australians have made many sacrifices during this pandemic, and they rightly expect the result of those sacrifices to be protected," Morrison said in a statement. "This is what the Minister is doing in taking this action today."

Everyone at the Australian Open -- including players, their support teams and spectators -- is required to be vaccinated for COVID-19. Djokovic is not inoculated and had sought a medical exemption on the grounds that he had COVID-19 in December.

That exemption was approved by the Victoria state government and Tennis Australia, apparently allowing him to obtain a visa to travel. But the Australian Border Force rejected the exemption and canceled his visa when he landed in Melbourne on Jan. 5.

Djokovic spent four nights in an immigration detention hotel before a judge on Monday overturned that decision. That ruling allowed Djokovic to move freely around Australia, and he has been practicing at Melbourne Park daily to prepare to play in a tournament he has won each of the past three years.

Australian Open organizers announced the top half of the men's and women's draws will be played Monday. That means Djokovic, the top seed, would have to play on Day 1 of the tournament.

He had a practice session scheduled for midafternoon Friday at Rod Laver Arena, the tournament's main stadium, but pushed that to the morning and was finished several hours before Hawke's decision was announced in the early evening.

After the visa cancellation, media started gathering outside the building where Djokovic reportedly was meeting with his lawyers.

An Australian Open spokesperson said tournament organizers did not have any immediate comment on the latest development in Djokovic's situation, which has overshadowed all other storylines heading into the year's first Grand Slam event.

"It's not a good situation for anyone," said Andy Murray, a three-time Grand Slam champion and five-time runner-up at the Australian Open. "Just want it obviously to get resolved. I think it would be good for everyone if that was the case. It just seems like it's dragged on for quite a long time now -- not great for the tennis, not great for the Australian Open, not great for Novak."

World No. 4 Stefanos Tsitsipas, speaking before Hawke's decision, said Djokovic was "playing by his own rules" and making vaccinated players "look like fools."

Tennis Australia announced that nine players would hold pre-tournament news conferences Saturday, and Djokovic's name was not on the list.

With his legal situation in limbo, Djokovic was placed in the tournament bracket in Thursday's draw, slated to face Miomir Kecmanovic in an all-Serbian matchup in the first round.

According to Grand Slam rules, if Djokovic is forced to pull out of the tournament before the order of play for Day 1 is announced, No. 5 seed Andrey Rublev would move into Djokovic's spot in the bracket and face Kecmanovic.

If Djokovic withdraws from the tournament after Monday's schedule is released, he would be replaced in the field by what's known as a "lucky loser" -- a player who loses in the qualifying tournament but gets into the main draw because of another player's exit before competition has started.

And if Djokovic plays in a match and then is told he can no longer participate in the tournament, his next opponent would simply advance to the following round and there would be no replacement.

Melbourne-based immigration lawyer Kian Bone said Djokovic's lawyers face an "extremely difficult" task to get court orders over the weekend to allow their client to play next week.

Speaking hours before Hawke's decision was announced, Bone said: "If you left it any later than he has done now, I think from a strategic standpoint, he's really hamstringing Djokovic's legal team, in terms of what sort of options or remedies he could obtain."

The Associated Press and Reuters contributed to this report.